.cb1r-lab-main { max-width: var(--container-max, 82rem); margin: 0 auto; padding: 2rem 1.25rem 5rem; }
.lab-section { padding: clamp(3rem, 7vw, 6rem) 0; border-bottom: 1px solid var(--line); }
.section-heading { max-width: 52rem; margin-bottom: 2rem; }
.section-heading h2 { margin: .35rem 0 1rem; color: var(--accent-strong); font-size: clamp(2rem, 4vw, 3.25rem); line-height: 1.08; }
.lab-contract-grid, .dynamics-compare-grid, .analysis-grid, .boundary-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 1rem; }
.lab-contract-grid--four { grid-template-columns: repeat(4, minmax(0, 1fr)); }
.mission-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 1rem; }
.mission-card { padding: 1.35rem; border: 1px solid var(--line); border-top: 3px solid var(--accent); border-radius: var(--radius); background: var(--accent-soft); }
.mission-card span { color: var(--accent); font-weight: 800; letter-spacing: .08em; }.mission-card h3 { margin: .7rem 0 .45rem; color: var(--accent-strong); }.mission-card p { margin: 0; }
.lab-contract-card, .dynamics-record, .analysis-grid article, .boundary-grid p, .docking-selector-card { padding: 1.35rem; background: var(--panel-soft); border: 1px solid var(--line); border-radius: var(--radius); }
.lab-contract-card span { color: var(--accent); font-weight: 800; letter-spacing: .1em; }
.lab-contract-card h3, .dynamics-record h3 { margin: .7rem 0 .45rem; color: var(--accent-strong); }
.mini-spec { display: grid; gap: .45rem; margin: 1rem 0 0; padding-top: .8rem; border-top: 1px solid var(--line); }
.mini-spec div { display: flex; justify-content: space-between; gap: 1rem; font-size: .86rem; }.mini-spec dt { color: var(--muted); }.mini-spec dd { margin: 0; color: var(--accent-strong); font-weight: 700; text-align: right; }
.workflow-tabs { display: grid; grid-template-columns: repeat(5, 1fr); gap: .55rem; margin-bottom: 1rem; }
.workflow-tabs button { min-height: 3.2rem; border: 1px solid var(--line); border-radius: var(--radius-sm); background: var(--panel); color: var(--accent-strong); font: inherit; font-weight: 700; cursor: pointer; }
.workflow-tabs button:hover, .workflow-tabs button:focus-visible, .workflow-tabs button.is-active { border-color: var(--accent); background: var(--accent-soft); outline: none; }
.workflow-panel { padding: clamp(1.5rem, 4vw, 3rem); border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); box-shadow: var(--shadow); }
.workflow-panel h3 { margin: .35rem 0 .75rem; color: var(--accent-strong); font-size: 1.6rem; }
.quality-gate { display: flex; gap: .75rem; align-items: baseline; margin-top: 1.5rem; padding-top: 1rem; border-top: 1px solid var(--line); }
.quality-gate strong { color: var(--accent); white-space: nowrap; }
.docking-selector-card { display: grid; grid-template-columns: minmax(13rem, .7fr) minmax(0, 1.3fr); gap: .65rem 1rem; align-items: center; margin-bottom: 1.25rem; min-width: 0; }
.docking-selector-card label { font-weight: 700; color: var(--accent-strong); }
.docking-selector-card select { width: 100%; min-width: 0; min-height: 2.8rem; padding: .5rem .7rem; border: 1px solid var(--line); border-radius: var(--radius-sm); background: #fff; color: var(--text); font: inherit; }
.docking-context { grid-column: 1 / -1; margin-top: .5rem; padding-top: 1rem; border-top: 1px solid var(--line); }
.docking-context h3 { margin: .35rem 0 .5rem; color: var(--accent-strong); }
.docking-context a, .module-link { display: inline-block; margin-top: .75rem; color: var(--accent-strong); font-weight: 700; text-decoration-thickness: .12em; text-underline-offset: .18em; }
.lab-table-wrap { overflow-x: auto; border: 1px solid var(--line); border-radius: var(--radius); }
.lab-table-wrap table { min-width: 42rem; }
.dynamics-compare-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); }
.dynamics-record--available { border-color: var(--accent); background: var(--accent-soft); }
.dynamics-record ul { margin: 1rem 0 0; padding-left: 1.15rem; }
.status-pill { display: inline-flex; margin-top: 1rem; padding: .25rem .6rem; border-radius: var(--radius-pill); font-size: .78rem; font-weight: 800; letter-spacing: .04em; }
.status-pill--planned { background: #fff1d7; color: #79500b; }
.analysis-grid { grid-template-columns: repeat(4, minmax(0, 1fr)); }
.analysis-grid article { display: grid; gap: .35rem; }
.analysis-grid strong { color: var(--accent-strong); }
.analysis-grid span { color: var(--muted); }
.boundary-grid { grid-template-columns: repeat(3, minmax(0, 1fr)); margin: 1.25rem 0; }
.boundary-grid p { border-left: 3px solid var(--accent); }
.case-study-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 1rem; }
.case-study-card { padding: 1.35rem; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel-soft); }
.case-study-card--observed { border-top: 3px solid var(--accent); }
.case-study-card--review { border-top: 3px solid #c8942e; }
.case-study-card h3 { margin: .7rem 0 .5rem; color: var(--accent-strong); }
.case-study-card ul { padding-left: 1.15rem; }
.case-study-note { margin-top: 1rem; padding: 1rem 1.2rem; border-left: 3px solid var(--accent); background: var(--accent-soft); }
.source-line { color: var(--muted); }
.visual-feature { display: grid; grid-template-columns: minmax(0, 1.35fr) minmax(16rem, .65fr); gap: 1rem; align-items: stretch; }
.visual-hero-card, .visual-gallery figure, .video-grid figure { margin: 0; overflow: hidden; border: 1px solid var(--line); border-radius: var(--radius); background: #061b1d; }
.visual-hero-card img { display: block; width: 100%; aspect-ratio: 1 / 1; object-fit: cover; }
.visual-hero-card figcaption, .visual-gallery figcaption, .video-grid figcaption { display: grid; gap: .2rem; padding: .9rem 1rem; color: #f4fff8; }
.visual-hero-card figcaption span, .visual-gallery figcaption span, .video-grid figcaption span { color: rgba(244, 255, 248, .72); font-size: .86rem; }
.visual-copy { display: flex; flex-direction: column; justify-content: center; padding: clamp(1.25rem, 3vw, 2.25rem); border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel-soft); }
.visual-copy h3 { margin: .35rem 0 .75rem; color: var(--accent-strong); }
.visual-legend { display: grid; gap: .6rem; margin-top: 1rem; color: var(--accent-strong); font-weight: 700; }
.visual-legend span { display: flex; align-items: center; gap: .55rem; }
.legend-swatch { display: inline-block; width: .85rem; height: .85rem; border-radius: 50%; }
.legend-swatch--membrane { background: #e5ed00; }.legend-swatch--receptor { background: #08c5cd; }.legend-swatch--ligand { background: #a8d247; }
.visual-gallery { display: grid; grid-template-columns: repeat(5, minmax(0, 1fr)); gap: 1rem; margin-top: 1rem; }
.visual-gallery img { display: block; width: 100%; aspect-ratio: 1 / 1; object-fit: contain; background: #000; }
.video-panel { margin-top: clamp(2rem, 5vw, 4rem); padding: clamp(1.25rem, 3vw, 2rem); border-radius: var(--radius); background: var(--accent-strong); color: #f4fff8; }
.video-panel .section-heading { margin-bottom: 1.25rem; }.video-panel .section-heading h3 { color: #f4fff8; }.video-panel .section-heading p { color: rgba(244, 255, 248, .78); }
.video-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 1rem; }.video-grid video { display: block; width: 100%; aspect-ratio: 16 / 9; object-fit: cover; background: #000; }
.evidence-grid { display: grid; grid-template-columns: repeat(4, minmax(0, 1fr)); gap: 1rem; margin-bottom: 1rem; }
.evidence-card { display: grid; gap: .35rem; padding: 1.35rem; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel-soft); }
.evidence-card--accent { border-top: 3px solid var(--accent); background: var(--accent-soft); }
.evidence-label, .evidence-register span { color: var(--accent); font-size: .76rem; font-weight: 800; letter-spacing: .08em; text-transform: uppercase; }
.evidence-card strong { color: var(--accent-strong); font-size: clamp(1.55rem, 3vw, 2.25rem); line-height: 1.1; }
.evidence-card p, .evidence-register p { margin: 0; color: var(--muted); }
.evidence-register { display: grid; grid-template-columns: repeat(4, minmax(0, 1fr)); gap: 1px; overflow: hidden; border: 1px solid var(--line); border-radius: var(--radius); background: var(--line); }
.evidence-register > div { display: grid; gap: .35rem; padding: 1.1rem; background: var(--panel); }
.evidence-register strong { color: var(--accent-strong); }
.npt-explorer { display: grid; grid-template-columns: minmax(15rem, .7fr) minmax(0, 1.3fr); gap: 1rem; align-items: stretch; }
.npt-control, .npt-metrics > div { padding: 1.2rem; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel-soft); }
.npt-control { display: grid; align-content: center; gap: .7rem; }.npt-control label { color: var(--accent-strong); font-weight: 800; }.npt-control input { width: 100%; accent-color: var(--accent); }.npt-range-labels { display: flex; justify-content: space-between; color: var(--muted); font-size: .8rem; }.npt-control output { color: var(--accent-strong); font-size: 1.15rem; font-weight: 800; }.npt-control p { margin: 0; color: var(--muted); font-size: .82rem; line-height: 1.55; }
.npt-metrics { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 1px; overflow: hidden; border: 1px solid var(--line); border-radius: var(--radius); background: var(--line); }.npt-metrics > div { border: 0; border-radius: 0; background: var(--panel); }.npt-metrics span, .npt-metrics small { display: block; color: var(--muted); }.npt-metrics strong { display: block; margin: .35rem 0; color: var(--accent-strong); font-size: clamp(1.25rem, 2.5vw, 1.8rem); }.npt-metrics small { font-size: .78rem; }
.maturity-track { display: grid; gap: .75rem; margin: 0; padding: 0; list-style: none; }
.maturity-step { display: grid; grid-template-columns: 4rem minmax(0, 1fr) auto; gap: 1rem; align-items: center; padding: 1rem 1.15rem; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel-soft); }
.maturity-step > span { display: grid; place-items: center; width: 3rem; height: 3rem; border-radius: 50%; background: var(--line); color: var(--accent-strong); font-weight: 800; }
.maturity-step strong { color: var(--accent-strong); }.maturity-step p { margin: .25rem 0 0; color: var(--muted); }.maturity-step b { padding: .25rem .6rem; border-radius: var(--radius-pill); background: var(--line); color: var(--muted); font-size: .75rem; white-space: nowrap; }
.maturity-step--complete { border-left: 3px solid var(--accent); }.maturity-step--complete > span, .maturity-step--current > span { background: var(--accent); color: #fff; }.maturity-step--complete b { background: var(--accent-soft); color: var(--accent-strong); }.maturity-step--current { border-left: 3px solid #c8942e; background: #fffaf0; }.maturity-step--current b { background: #fff1d7; color: #79500b; }
.method-disclosure { margin-top: 1rem; border: 1px solid var(--line); border-radius: var(--radius); background: var(--panel); }.method-disclosure summary { cursor: pointer; padding: 1rem 1.15rem; color: var(--accent-strong); font-weight: 800; }.method-disclosure > div { padding: 0 1.15rem 1rem; }.method-disclosure pre { overflow-x: auto; padding: 1rem; border-radius: var(--radius-sm); background: #061b1d; color: #c8f5df; }.method-disclosure code, .method-disclosure pre code { color: #c8f5df; font: .86rem/1.6 ui-monospace, SFMono-Regular, Menlo, monospace; }
@media (max-width: 800px) { .lab-contract-grid, .analysis-grid, .boundary-grid, .case-study-grid, .evidence-grid, .evidence-register, .mission-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); } .workflow-tabs { grid-template-columns: repeat(2, 1fr); } }
@media (max-width: 800px) { .visual-feature, .visual-gallery, .video-grid { grid-template-columns: repeat(2, minmax(0, 1fr)); } .visual-hero-card { grid-column: 1 / -1; } }
@media (max-width: 560px) { .cb1r-lab-main { padding-inline: 1rem; } .lab-contract-grid, .dynamics-compare-grid, .analysis-grid, .boundary-grid, .case-study-grid, .evidence-grid, .evidence-register, .visual-feature, .visual-gallery, .video-grid, .mission-grid { grid-template-columns: 1fr; } .quality-gate { display: grid; gap: .25rem; } .visual-hero-card { grid-column: auto; } .maturity-step { grid-template-columns: 3rem minmax(0, 1fr); }.maturity-step > span { width: 2.7rem; height: 2.7rem; }.maturity-step b { grid-column: 2; justify-self: start; } }
@media (max-width: 800px) { .npt-explorer { grid-template-columns: 1fr; } }
@media (max-width: 560px) { .npt-metrics { grid-template-columns: 1fr; } }
@media (prefers-reduced-motion: reduce) { .lab-hero video { display: none; } }