Kannabium · AI agentSec

SEC · SCIENTIFIC CURATION · EVIDENCE MANAGEMENT

Sec · AI agent for scientific evidence curation and analysis

Sec is being developed to support source selection, metadata normalization, and evidence review. The interface is available; the runtime is planned. Automated services and connectors require implementation and testing. The proposed publication workflow requires human review and links claims to methods and sources.

Sec before holographic panels connecting plants, animals, and scientific data
Editorial illustration of plants, animals, and scientific data

01 · PROPOSED CAPABILITIES

Planned Sec functions from collection to publication

The proposed workflow covers collection, normalization, validation, interpretation, review, and publication. Each stage should record inputs, decisions, versions, and responsible parties to distinguish observed data, inferences, hypotheses, and recommendations. The cards describe planned tasks; they do not confirm deployed services.

PLANNED CAPABILITY 01

Scientific curation

Record primary and secondary sources with identifiers, authorship, date, method, version, scope, and conditions of use.

  • DOI, PMID, taxonomy, and persistent identifiers
  • source scope, method, date, and version
  • evidence grade and interpretive limits
PLANNED CAPABILITY 02

Data integration

Standardize and combine datasets to compare entities and identify associations without treating them as causal relations.

  • question-led acquisition and cleaning
  • feature construction and analytical matrices
  • hypotheses separated from observed results
PLANNED CAPABILITY 03

Evolutionary bioinformatics

Analyze relations among taxa, genes, proteins, and metabolites with methods from systematics, phylogeny, and comparative genomics.

  • relations among taxa and characters
  • uncertainty, support, and method choice
  • results prepared for consultation and review
PLANNED CAPABILITY 04

Traceability and governance

Record the origin, transformations, relations, and versions of data between source and publication.

  • entity, evidence, relation, and version
  • controlled vocabulary and canonical names
  • explicit record of what cannot be concluded
PLANNED CAPABILITY 05

Data and interface publication

Prepare pages, dashboards, charts, and structured packages for databases or APIs from reviewed content.

  • editorial hierarchy and accessibility
  • data that remains readable without JavaScript
  • separation of content, visualization, and interaction
PLANNED CAPABILITY 06

Critical review

Challenge extrapolations, compare sources, and state when a conclusion depends on inference.

  • comparison across sources and methods
  • gap and conflict detection
  • recommendations proportional to evidence
PLANNED CAPABILITY 07

Source selection and registration

Select authoritative sources and record why each source is relevant to the question.

  • source priority and access route
  • scope, rights, and update status
  • retrieval decisions with provenance
PLANNED CAPABILITY 08

Semantic normalization

Reconcile names, identifiers, units, and controlled vocabularies across heterogeneous records.

  • canonical names and synonyms
  • identifier mapping
  • unit and field consistency
PLANNED CAPABILITY 09

Evidence grading

Distinguish experimental evidence, review, inference, hypothesis, and recommendation.

  • claim-to-source mapping
  • methodological strength
  • confidence and limitation labels
PLANNED CAPABILITY 10

Taxonomic resolution

Resolve accepted names, synonyms, taxon scope, and classification before biological comparison.

  • taxon identity and authority
  • lineage-aware comparisons
  • classification versioning
PLANNED CAPABILITY 11

Phylogenetic analysis

Prepare alignments, infer trees, and record support values, methods, and analytical uncertainty.

  • character and sequence evidence
  • method selection
  • interpretation within scope
PLANNED CAPABILITY 12

Comparative genomics

Compare genes, proteins, orthologs, and genomic regions while preserving version context.

  • homology and orthology
  • genome and sequence relations
  • reproducible comparison inputs
PLANNED CAPABILITY 13

Literature synthesis

Compare studies and produce citation-linked summaries while preserving differences in method, sample, and population.

  • study design comparison
  • claim clustering
  • citation-aware synthesis
PLANNED CAPABILITY 14

Hypothesis management

Record hypotheses, assumptions, predictions, and tests as distinct scientific objects.

  • assumption register
  • prediction and counterexample
  • hypothesis status
PLANNED CAPABILITY 15

Data modeling

Represent entities, relations, and provenance in schemas, matrices, knowledge graphs, and API records.

  • entity and relation design
  • field-level provenance
  • structured publication packages
PLANNED CAPABILITY 16

Agent evaluation

Check whether outputs cite sources, answer the question, follow the defined format, and can be reproduced.

  • question-to-answer test cases
  • failure and drift detection
  • human review checkpoints
PLANNED CAPABILITY 17

Security and privacy

Apply controls to prevent secrets and private context from entering public products by default.

  • backend-only credentials
  • explicit context boundaries
  • least-privilege distribution
PLANNED CAPABILITY 18

Observability and audit

Record runs, inputs, versions, decisions, and publication state to support auditing and reproduction.

  • execution lineage
  • contract and policy checks
  • reviewable audit trail
PLANNED CAPABILITY 19

Scientific communication

Present reviewed results with audience-appropriate language, citations, limitations, and a clear visual hierarchy.

  • audience-aware language
  • visual and semantic hierarchy
  • claim-preserving summaries
PLANNED CAPABILITY 20

Workflow design

Define a reproducible sequence from question and source selection through analysis, review, and delivery.

  • task decomposition
  • handoff contracts
  • reusable operating patterns

02 · WORKFLOW

Proposed coordination of tasks and results

For requests requiring different specialties, the planned workflow would define stages, select agents, check their results, and assemble a deliverable for human review.

Define the question

Define the question, organism, domain, time scale, and decision the result should support.

Select agents

Activate curation, evolution, data, security, product, or QA agents according to the task.

Validate results

Compare responses, identify conflicts, check cited evidence, and record uncertainty.

Record and deliver

Prepare the response, record, interface, or data package with documented sources, versions, and decisions.

GOVERNING RULE

Link each claim to its corresponding source.

The workflow should record information sources and distinguish observed data, interpretations, hypotheses, and recommendations.

03 · SOURCES AND CONNECTORS

Scientific sources proposed for Sec integration

The proposed connectors would query sources, standardize retrieved records, and preserve identifiers. Each integration must report its deployment status and tested version, and respect access permissions, usage rights, rate limits, and attribution rules. Listing a source does not confirm an active connector.

Literature

PubMed · DOI · OpenAlex

Locate articles, reviews, metadata, authors, identifiers, and bibliographic relations.

  • source_id
  • publication_date
  • method_scope
Taxonomy

NCBI · IPNI · Kew

Check accepted names, synonyms, authors, lineages, and taxonomic identifiers.

  • taxon_id
  • accepted_name
  • classification
Genomics

NCBI · GenBank · RefSeq

Query sequences, assemblies, genes, and genomic regions while preserving the record identifier and version.

  • accession
  • sequence_scope
  • version
Proteins

UniProt · Ensembl · OrthoDB

Connect proteins, orthology, annotated function, experimental evidence, and evolutionary comparison.

  • protein_id
  • evidence_code
  • orthology_relation
Structures

PDB · AlphaFold DB

Relate structures, ligands, residues, conformational states, and predicted models with their limitations.

  • structure_id
  • experimental_method
  • model_status
Chemistry and health

PubChem · ChEMBL · institutions

Organize compounds, bioactivity, and health indicators without mixing molecule, product, market, and population.

  • compound_id
  • assay_context
  • population_scope
Bibliographic metadata

Crossref · Europe PMC

Resolve DOI metadata, abstracts, full-text links, publication status, and citation context.

  • doi
  • abstract_status
  • full_text_route
Sequence archives

ENA · SRA

Connect raw reads, projects, samples, and study context while respecting controlled-access boundaries.

  • run_accession
  • sample_id
  • access_policy
Functional annotation

InterPro · Pfam

Relate protein domains, families, conserved regions, and functional interpretation.

  • domain_id
  • family_id
  • annotation_evidence
Pathways

KEGG · Reactome

Map pathways, reactions, organism context, and molecular processes to biological entities.

  • pathway_id
  • reaction_id
  • organism_scope
Interaction networks

STRING

Connect protein associations while keeping experimental, curated, co-expression, and predicted channels distinct.

  • protein_pair
  • evidence_channel
  • confidence_score
Gene expression

GEO

Query series, samples, platforms, study designs, and information about data processing.

  • series_id
  • sample_id
  • platform
Biodiversity

GBIF · iNaturalist

Organize occurrence records, coordinates, observation uncertainty, and taxonomic context.

  • occurrence_id
  • geospatial_scope
  • observation_quality
Public health

EUDA · WHO · FDA

Separate institutional indicators, regulatory records, population scope, and policy interpretation.

  • indicator_id
  • jurisdiction
  • interpretive_boundary
Germplasm

GRIN · Genesys

Connect accessions, germplasm records, material context, and collection metadata.

  • accession_id
  • material_type
  • collection_context

04 · PROPOSED ARCHITECTURE

Components and controls in Sec's architecture

The proposal separates scientific rules, the installable package, source adapters, and consuming projects. This division allows each component to be versioned and limits the data and functions available to each project.

LAYER 01 · CANONICAL CORE

Scientific and governance rules

The planned core would contain capabilities, contracts, policies, vocabularies, and records that should remain consistent across Sec versions.

{ skills, contracts, policies, registry }
LAYER 02 · DISTRIBUTION

Installable package

The planned package would define product metadata, interface, capability status, version, and agent activation conditions.

plugin.manifest(capabilities, interface, version)
LAYER 03 · ADAPTERS

Source adapters

The proposed adapters would convert data from Kannabium, plant_connectors_core, and bibliographic services into the contracts defined by the core.

adapter.connect(source, contract, policy)
LAYER 04 · PROJECTS

Authorized projects

Each project should receive only approved functions and contexts. Access to private data must be explicit, limited, and recorded.

project.consume(plugin, approved_context)

ACADEMIC AND COMMERCIAL APPLICATION

The proposed model requires evidence traceability and access controls.

In research projects, the planned workflow would link each result to its source, method, version, uncertainty, and applied taxonomic identification. The four proposed layers would separate the scientific core from distributed components, with rules for licensing, integration, access, and new domains. Access to private context would require explicit project authorization.